Eales Disease

Important Percentages

• NVI: 0.5-0.8 %
• NVD: 10-18 %
• NVE: 50 %
• Sec RRD: 8-11 %

Proliferative vascular retinopathy mimicking eales

• SYSTEMIC: DM, Sarcoidosis, Sickle
• OCULAR: BRVO, CRVO, Coats, Pars Planitis, ROP

Main causes of vision loss in Eales’ Disease

• SUDDEN
• Vitreous hemorrhage (NVE, Inflammatory BRVO, NVD)
• Secondary rhegmatogenous retinal detachment

GRADUAL

• Macular edema
• Traction retinal detachment involving posterior pole
• Disc edema
• Multiple vitreous membranes
• Cataract
• Glaucoma – NVG/Ghost cell
• Optic atrophy
• Epimacular membrane

Main indications for vitrectomy in Eales’ disease

• Non-resolving vitreous hemorrhage
• Traction retinal detachment involving posterior pole
• Multiple vitreous membranes
• Combined traction and rhegmatogenous retinal detachment
• Vitreous hemorrhage associated with hemolytic or ghost-cell glaucoma
• Macular pucker / Epimacular membrane
• Vitreous hemorrhage associated with rubeosis

Management

• If B/L: Systemic Steroids
• If U/L:
• <2 quadrent: PST
          
• >2 quadrent: Systemic Steroids

- compiled & published by Dr Dhaval Patel MD AIIMS